What is the target goal of stimulus to RWPT in LBBB patients?

In patients with left bundle branch block (LBBB), the goal of pacing, particularly in relation to achieving effective resynchronization, is to minimize the time interval between the pacing stimulus and the right ventricular pacing site (RWPT). A target of less than 80 milliseconds is considered optimal for ensuring that the electrical impulses reach their destination quickly enough to promote coordinated contraction of the heart chambers.

Setting the pacing threshold at less than 80 milliseconds helps to reduce the risk of dyssynchrony, which can occur if the electrical impulse experiences delays. In LBBB, the conduction pathway is already compromised, so maintaining a brief stimulus to RWPT is crucial for enhancing cardiac function and improving hemodynamics. The performance of pacing within this time frame is associated with better clinical outcomes, as it allows for more effective synchronization of ventricular contractions, leading to improved cardiac efficiency and symptom relief in patients.

Other targets may be related to similar physiological objectives but do not provide the same balance of efficiency and effectiveness as the less than 80 milliseconds benchmark.